Syrup in development · Private label
Cough and sore throat syrupSugar-free
preservative-free
Soothing the throat and helping remove mucus in a sugar-free, preservative-free formulation. Vitrobio is developing a syrup for dry cough, productive cough and sore throat. Based on our patented film-forming glycerol technology, it combines throat protection with action that promotes mucus hydration while preserving the protective cough reflex.
The formulation presented is being developed for adults and children aged 2 and over, with lemon flavour and a volume of 120 ml. It is part of a range that can accommodate partners' needs: several versions are possible depending on formulation preferences, flavours and the intended population. This private-label offering draws on Vitrobio's experience using its technology in sprays.
Your syrup range,
under your brand
Clinical programme in progress
Planned randomised placebo-controlled study in 140 patients.
Intended population
Adults and children aged 2 and over.
Indication in development
Relief of dry cough, productive cough and sore throat, in development.
Benefits
for patients
- Immediate action (osmotic mechanical action).
- Forms a protective film on the throat.
- Helps soothe throat irritation.
- Helps thin mucus and facilitate its removal.
- Preserves the protective cough reflex.
- Sugar-free.
- Preservative-free.
Mode of action
The syrup deposits a film on the throat surface. Film-forming glycerol combines protection, hydration and osmotic cleansing: these functions act simultaneously, with two complementary benefits.
Soothing throat pain and irritation. The film forms a barrier that limits direct contact between irritants and the sensitive surface. Hydration contributes to throat comfort, while osmotic action attracts fluids towards the film and helps mobilise and remove irritants from the surface. These actions help soothe the throat and reduce irritation-related urges to cough.
Helping remove mucus. Hydration makes mucus easier to mobilise and expectorate. The syrup thus supports its natural removal without blocking the protective cough reflex.
Osmotic mechanical action starts immediately on contact with the surface. The film acts locally, without polymers penetrating the tissues.
Clinical programme · In progress
Clinical programme
A clinical programme focusing on cough and sore throat relief is underway. The randomised placebo-controlled study plans to enrol 140 patients, with an initial assessment at two minutes. This is the first measurement time point in the protocol.
The evaluation covers three practical dimensions:
- Cough: its severity and frequency.
- Throat comfort: pain, irritation and discomfort when swallowing.
- Daily life: quality of life and the impact of pain.
Development aims for a formulation that is gentle on the throat, with tolerability included in the clinical evaluation.
Detailed information on the development programme is available on request under a non-disclosure agreement.
Manufacturing & quality
Manufactured in France
Manufactured in-house at the Vitrobio laboratory.
ISO 13485
Quality management system certified by GMED.
Product details
| Field | Value |
|---|---|
| Public name | Cough and sore throat syrup |
| Product type | Syrup being developed as a medical device |
| Intended regulatory class | Class IIa |
| Intended regulatory framework | Regulation (EU) 2017/745 on medical devices |
| Vitrobio's notified body | GMED |
| Intended population / age | Adults and children aged 2 and over |
| Category | Cough and sore throat |
| Indication in development | Relief of dry cough, productive cough and sore throat |
| Composition | Film-forming glycerol |
| Formulation features | Sugar-free, preservative-free |
| Flavour | Lemon |
| Format / volume | 120 ml syrup, with carton and instructions for use |
| Target shelf life before opening | Development target: 3 years |
| Country of manufacture | France, manufactured in-house |
| Quality system | Quality management system certified to ISO 13485 by GMED |
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