PILESEPTINE GEL: A Revolutionary Approach to Internal Hemorrhoids Treatment

PILESEPTINE GEL is a Class IIa medical device designed as a filmogen liquid bandage for the treatment of internal hemorrhoids. The gel provides a protective barrier, osmotic cleaning, and promotes cellular repair. Clinical trials have shown significant improvements in symptoms such as pain intensity, rectal bleeding, prolapse extent, defecation discomfort, and irritation after defecation, with noticeable results appearing as early as 2 days into the treatment.

PILESEPTINE GEL: Innovative Treatment for Internal Hemorrhoids

Introduction to PILESEPTINE GEL

Introducing PILESEPTINE GEL, a Class IIa medical device specifically designed to provide relief and treatment for internal hemorrhoids, also known as piles. This innovative product offers a unique three-fold action to alleviate the discomfort and symptoms associated with internal hemorrhoids.

Targeted Proteins and Actions of PILESEPTINE GEL

PILESEPTINE GEL targets pro-inflammatory proteins, contaminants, and impurities, providing a comprehensive approach to hemorrhoid treatment.

Protective Barrier Effect

The gel acts as a protective barrier, shielding the inflamed area from further irritation and damage. This barrier also helps to prevent the adhesion of contaminants and impurities that can exacerbate inflammation and discomfort.

Osmotic and Cleaning Effect

The high osmotic activity of the gel instantly attracts and traps most of the adhered contaminants, including inflammatory proteins. This action helps to suppress inflammation and the immune cascade, providing immediate relief from discomfort.

Cellular Repair and Growth Effect

Once the biological surface is clean and hydrated, cell growth and healing are immediately triggered. This promotes the repair of the damaged tissue, further alleviating the symptoms of internal hemorrhoids.

Clinical Study and Results

The effectiveness of PILESEPTINE GEL has been confirmed through a randomized, double-blind, placebo-controlled trial over a period of 2 weeks. The study involved 54 patients, with 36 using the test product and 18 using the comparator.

Key Findings

The main results of the study were as follows:

Pain intensity was significantly reduced within 14 days.
Rectal bleeding was notably reduced within the same period.
The extent of prolapse was reduced within 14 days.
Defecation discomfort improved within 14 days.
Irritation after defecation was significantly reduced within 14 days.

These results clearly demonstrate the effectiveness of PILESEPTINE GEL in providing relief and promoting healing in patients suffering from internal hemorrhoids. The product was well-tolerated with no recorded side effects, making it a safe and effective option for hemorrhoid treatment.

A Comprehensive Guide to Hemorrhoids: Understanding, Causes, and Innovative Treatments

Understanding Hemorrhoids

Hemorrhoids, also known as piles, are a common condition characterized by the swelling and inflammation of the veins in the rectum and anus. They can be internal or external, with internal hemorrhoids developing inside the rectum and external ones under the skin around the anus.

Internal Hemorrhoids: Symptoms and Discomfort

Internal hemorrhoids, the type targeted by the PILESEPTINE GEL, are usually painless but can cause discomfort and bleeding during bowel movements. They can also prolapse, meaning they extend out of the anus, leading to additional symptoms such as irritation and mucus discharge.

Causes of Hemorrhoids

The exact cause of hemorrhoids is not fully understood, but they are associated with increased pressure in the lower rectum. This can occur due to a variety of factors including straining during bowel movements, sitting for long periods of time, especially on the toilet, chronic constipation or diarrhea, obesity, and pregnancy.

Prevalence and Treatment of Hemorrhoids

Hemorrhoids are very common, particularly during pregnancy and in older adults. While they can be uncomfortable and even painful, they are usually not serious and can be effectively treated with over-the-counter remedies, lifestyle changes, and medical procedures in more severe cases.

PILESEPTINE GEL: A Comprehensive Approach to Hemorrhoid Treatment

The PILESEPTINE GEL is designed to provide a protective barrier, clean the affected area through osmotic action, and promote cellular repair and growth. This offers a comprehensive approach to the treatment of internal hemorrhoids.

CLAIMS IN LINE WITH THE NEW REGULATION

Reduces pain intensity
Reduce rectal bleeding
Prevents hemorrhoid proliferation
Reduce irritation
Promotes the regression of hemorrhoids
Reduces discomfort during defecation
Mechanical mode of action
Instant osmotic action or Clinical effects from 24h
Hydrates, protects and cleanses
No preservatives
Clinically proven
Ingredients of natural origin
Patented technology

PILESEPTINE GEL: A Revolutionary Approach to Internal Hemorrhoids Treatment

General informations

Title : linical Efficacy of a New Generation of Multi-Target, Anti-Edematous, AntiInflammatory, Tissue Repairing Topical Polymeric Liquid Bandage for the Treatment of Internal Hemorrhoids

Journal : Clinical trials | 2017

Patients: N=54 | Test product = 36 ; Comparator = 18

Duration : 2 Weeks

Inclusion : having clinical manifestations of grade I to III internal hemorrhoids

LINK : 11-Int.-Hemorrhoids-J-Clin-Exp-Dermato-Res-072017

Main results

Pain Intensity

• 24 % reduction in pain intensity within 3 days, compare to CP
• 38 % reduction in pain intensity within 8 days, compare to CP
• 51 % reduction in pain intensity within 14 days, compare to CP

Bleeding

• 9 % reduction in rectal bleeding within 2 days, compare to CP
• 22 % reduction in rectal bleeding within 3 days, compare to CP
• 33 % reduction in rectal bleeding within 8 days, compare to CP
• 49 % reduction in rectal bleeding within 14 days, compare to CP

Extend of prolapse

• 5 % reduction in the extend of prolapse within 2 days.
• 13 % reduction in the extend of prolapse within 3 days.
• 22 % reduction in the extend of prolapse within 8 days.
• 27 % reduction in the extend of prolapse within 14 days.

Defecation discomfort

• 18 % improvement in defecation discomfort within 2 days.
• 35,5 % improvement in defecation discomfort within 3 days.
• 52,6 % improvement in defecation discomfort within 8 days.
• 69,7 % improvement in defecation discomfort within 14 days.

Indication	Filmogen liquid bandage for the treatment of internal hemorrhoids (piles).
Composition	Filmogenic glycerol, water, association of Vaccinium macrocarpon, Vitris vinifera, EO : Mentha piperita and Linum Usitatissimum oil.
Presentation	Tube 50ml - Classe IIa
Class	MDD Class IIa \| MDR Class IIa
Direction	Apply in wounds, 2-3 times a day
Precautions	For topical use only (nasal cavity). Keep out of reach and sight of children.
Age	18+
Storage conditions	Below 25°C
Legal manufacturer	VITROBIO (France)
Product code	PII