NESOSPRAY HE-G: Advanced Nasal Spray for Effective Relief from Rhinosinusitis, Rhinitis, and Nasal Congestion
NESOSPRAY HE-G from Vitrobio is an innovative nasal spray designed for the treatment of rhinosinusitis, rhinitis, and nasal congestion in individuals aged 3 years and above. It works by creating a filmogenic liquid bandage on the nasal mucosal surface, providing hydration, cleansing, and reducing contaminants and pro-inflammatory proteins through osmotic action. This osmotic action also helps to massively unblock congested sinuses, providing immediate relief. The spray further promotes cell growth and repair, allowing the nasal mucosa to regenerate and regain its integrity. A clinical trial is currently underway, with results expected in January 2024.
Introducing NESOSPRAY HE-G
Vitrobio presents NESOSPRAY HE-G, a novel solution specifically designed for the treatment of rhinosinusitis, rhinitis, and nasal congestion. This product is a nasal spray in a convenient 15 ml format, designed for easy application and optimal delivery of the active components. It is suitable for use in individuals aged 3 years and above.
Targeted Proteins and Actions
1. Protective Barrier Effect: NESOSPRAY HE-G works by creating a filmogenic liquid bandage on the nasal mucosal surface. This protective barrier shields the nasal mucosa from further irritation or infection, providing an immediate layer of defense.
2. Osmotic Action: The spray also exerts an osmotic action, which attracts fluids towards the exterior, helping to massively unblock congested sinuses. This osmotic action also cleanses the nasal mucosa by effectively drawing out contaminants, debris, and pro-inflammatory proteins such as cytokines and interleukins. This dual action of unblocking and cleansing provides immediate relief and creates a clean environment conducive to healing.
3. Cellular Repair and Growth Effect: With the nasal mucosa now in a clean and protected state, the healing process can effectively begin. The spray promotes cell growth and repair, allowing the nasal mucosa to regenerate and regain its integrity. This restoration of the nasal mucosa is crucial for long-term relief from rhinosinusitis, rhinitis, and nasal congestion.
In conclusion, NESOSPRAY HE-G represents a significant advancement in the treatment of rhinosinusitis, rhinitis, and nasal congestion. Its unique mechanism of action, combined with its ease of use and the promising results from previous similar products, make it a promising addition to the therapeutic options available for these common conditions.
Understanding Rhinosinusitis, Rhinitis, and Nasal Congestion
Rhinosinusitis, rhinitis, and nasal congestion are common health issues that can significantly affect individuals’ comfort and quality of life. These conditions are characterized by inflammation and swelling in the nose and sinuses, leading to symptoms such as a runny or stuffy nose, sneezing, and facial pain or pressure.
Causes and Symptoms of Rhinosinusitis, Rhinitis, and Nasal Congestion
These conditions can be caused by various factors, including viral infections (like the common cold or flu), allergies, and environmental irritants. In individuals of all ages, these conditions can also be exacerbated by factors such as exposure to secondhand smoke, changes in weather, or underlying health conditions like asthma.
The symptoms of rhinosinusitis, rhinitis, and nasal congestion can be particularly bothersome, affecting sleep, productivity, and overall quality of life. These symptoms can also lead to other complications, such as sinusitis or ear infections, if not properly treated.
Treatment for Rhinosinusitis, Rhinitis, and Nasal Congestion
Treatment for these conditions typically involves managing the symptoms and addressing the underlying cause. This can include the use of over-the-counter remedies, prescription medications, and in some cases, lifestyle changes or procedures. It’s important for individuals to consult with a healthcare provider to determine the best course of treatment for their condition.
Prevention of Rhinosinusitis, Rhinitis, and Nasal Congestion
Prevention strategies include regular hand washing, avoiding known allergens, and maintaining a healthy indoor environment. Regular check-ups with a healthcare provider can also help detect and manage these conditions early.
Rhinosinusitis, rhinitis, and nasal congestion can significantly impact an individual’s wellbeing. Understanding these conditions, their causes, symptoms, and treatment options can help individuals seek timely medical care and manage their symptoms effectively. With the right treatment, such as NESOSPRAY HE-G, individuals can find relief from these common conditions and enjoy a better quality of life.
CLAIMS IN LINE WITH THE NEW REGULATION
- Mechanical mode of action
- Instant osmotic action
- Clears, decongests and cleanses the sinuses
- Dual action: Relieves and protects
- Reduces contaminants on the nasal surface
- Reduces nasal congestion, sinus pain
- Reduce all the rhinosinusitis symptoms
- No drowsiness . No habituation effect
- Fast action
Clinical Trials and Expected Results
A randomized, double-blind clinical trial against a placebo is currently underway to evaluate the effectiveness of NESOSPRAY HE-G. The trial is expected to conclude in January 2024 and includes 46 patients, with a treatment duration of 14 days. The trial also includes children from the age of 3 and pregnant women.
While the results of this specific trial are not yet available, previous trials on similar Vitrobio formulations for rhinosinusitis have shown very promising results. These include a 30% reduction in nasal congestion within 30 minutes and a 59% reduction in all rhinosinusitis symptoms within just 1 day of treatment. Similar results are expected for NESOSPRAY HE-G.
The main objective of the current trial is to evaluate the evolution of rhinorrhea symptoms 2 hours after the first use of the treatment compared to the placebo group. Secondary objectives include evaluating the evolution of rhinorrhea symptoms at 1, 3, 6, and 14 days of treatment, the use of antibiotic therapy between the two groups, and the safety and side effects of the product.
|Indication||Filmogen liquid bandage for the treatment of rhinosinusitis, rhinitis and nasal congestion.|
|Composition||Filmogenic glycerol, HPC, water, association of Vaccinium macrocarpon, Camellia sinensis, Vaccinium myrtillus, Sambucus nigra. EO : Mentha, Eucalypt, Thym and Rosmar.|
|Presentation||Nasal spray 15ml|
|Class||MDD Class I | MDR Class IIa|
|Direction||Apply 2 sprays in each nostril, 2-3 times a day|
|Precautions||For topical use only (nasal cavity). Keep out of reach and sight of children.|
|Storage conditions||Below 25°C|
|Legal manufacturer||VITROBIO (France)|